diff --git a/chrome/content/zotero/standalone/standalone.js b/chrome/content/zotero/standalone/standalone.js
index 0d3677e356..0fa63c7207 100644
--- a/chrome/content/zotero/standalone/standalone.js
+++ b/chrome/content/zotero/standalone/standalone.js
@@ -962,6 +962,26 @@ function toJavaScriptConsole() {
 }
 
 function launchDeveloperToolbox() {
+	let prefs = ['devtools.chrome.enabled', 'devtools.debugger.remote-enabled'];
+	let enabled = prefs.every(pref => !!Zotero.Prefs.get(pref, true));
+	if (!enabled) {
+		let ps = Services.prompt;
+		let shouldEnable = ps.confirm(
+			null,
+			'Remote Debugging Disabled',
+			'Enable remote debugging? This will allow Firefox instances on this machine to control ' + Zotero.appName + '.'
+				+ '\n\nThis is inherently a security risk and is NOT RECOMMENDED for normal use.'
+		);
+		if (shouldEnable) {
+			for (let pref of prefs) {
+				Zotero.Prefs.set(pref, true, /* global */ true);
+			}
+		}
+		else {
+			return;
+		}
+	}
+	
 	const { BrowserToolboxLauncher } = ChromeUtils.import("resource://devtools/client/framework/browser-toolbox/Launcher.jsm");
 	// Don't launch if already open
 	// (Can we focus the existing toolbox process?)