diff --git a/litellm/integrations/newrelic/newrelic.py b/litellm/integrations/newrelic/newrelic.py
index 2117ea48604..e0e61e9cacd 100644
--- a/litellm/integrations/newrelic/newrelic.py
+++ b/litellm/integrations/newrelic/newrelic.py
@@ -117,6 +117,12 @@ class NewRelicLogger(CustomLogger):
                     "Integration will be disabled."
                 )
                 self.enabled = False
+            except Exception as e:
+                verbose_logger.error(
+                    f"Failed to initialize New Relic agent: {e}. "
+                    "Integration will be disabled."
+                )
+                self.enabled = False
 
     def _get_newrelic_params(self) -> Dict:
         """
diff --git a/tests/test_litellm/integrations/newrelic/test_newrelic.py b/tests/test_litellm/integrations/newrelic/test_newrelic.py
index d2dce43bd8a..166fec98b93 100644
--- a/tests/test_litellm/integrations/newrelic/test_newrelic.py
+++ b/tests/test_litellm/integrations/newrelic/test_newrelic.py
@@ -126,6 +126,16 @@ class TestNewRelicLoggerInit:
                 logger = NewRelicLogger()
         assert logger.enabled is False
 
+    def test_disabled_on_agent_startup_error(self):
+        with patch.object(
+            _mock_newrelic_agent,
+            "register_application",
+            side_effect=RuntimeError("agent startup failed"),
+        ):
+            with patch.dict(os.environ, NR_ENV):
+                logger = NewRelicLogger()
+        assert logger.enabled is False
+
     def test_record_content_default_true(self):
         logger = make_logger()
         assert logger.record_content is True