diff --git a/litellm/llms/anthropic/chat/transformation.py b/litellm/llms/anthropic/chat/transformation.py
index 1f405de9817..2194b384a23 100644
--- a/litellm/llms/anthropic/chat/transformation.py
+++ b/litellm/llms/anthropic/chat/transformation.py
@@ -2109,6 +2109,11 @@ class AnthropicConfig(AnthropicModelInfo, BaseConfig):
         """Anthropic reports prompt cache tokens as top-level ``cache_read_input_tokens`` /
         ``cache_creation_input_tokens``; no other API surface uses those keys, and the
         Responses API mapping would silently drop them.
+
+        Requiring a cache key is deliberate: Responses API usage also carries top-level
+        ``input_tokens``, so the cache keys are the only shape discriminator between the
+        two. A cache-free Anthropic payload falls through to the Responses API mapping,
+        which is safe because both mappings agree whenever no cache tokens are present.
         """
         if "prompt_tokens" in usage_object or "input_tokens" not in usage_object:
             return False
diff --git a/tests/test_litellm/llms/anthropic/chat/test_anthropic_chat_transformation.py b/tests/test_litellm/llms/anthropic/chat/test_anthropic_chat_transformation.py
index 34fbea95e5b..231d3b48754 100644
--- a/tests/test_litellm/llms/anthropic/chat/test_anthropic_chat_transformation.py
+++ b/tests/test_litellm/llms/anthropic/chat/test_anthropic_chat_transformation.py
@@ -5867,3 +5867,19 @@ def test_is_anthropic_usage_object_distinguishes_chat_usage():
         ).model_dump()
     )
     assert not AnthropicConfig.is_anthropic_usage_object({"input_tokens": 3, "output_tokens": 5})
+
+
+def test_is_anthropic_usage_object_rejects_responses_api_usage():
+    """completion_cost checks the Anthropic shape before the Responses API shape, so a
+    Responses API usage payload, whose cache reads live in nested input_tokens_details,
+    must never match; matching would route it past the converter that reads the nested
+    field and its cache reads would be billed at the full input rate."""
+    assert not AnthropicConfig.is_anthropic_usage_object(
+        {
+            "input_tokens": 4017,
+            "output_tokens": 5,
+            "total_tokens": 4022,
+            "input_tokens_details": {"cached_tokens": 4014},
+            "output_tokens_details": {"reasoning_tokens": 0},
+        }
+    )
diff --git a/tests/test_litellm/llms/anthropic/experimental_pass_through/responses_adapters/test_responses_adapters_transformation.py b/tests/test_litellm/llms/anthropic/experimental_pass_through/responses_adapters/test_responses_adapters_transformation.py
index 77b6f902368..a268bdb640c 100644
--- a/tests/test_litellm/llms/anthropic/experimental_pass_through/responses_adapters/test_responses_adapters_transformation.py
+++ b/tests/test_litellm/llms/anthropic/experimental_pass_through/responses_adapters/test_responses_adapters_transformation.py
@@ -989,6 +989,13 @@ class TestTranslateResponse:
             "cache_read_input_tokens": 4004,
         }
 
+    def test_missing_usage_maps_to_zero_tokens(self):
+        """A response without a usage object must map to zeroed Anthropic usage."""
+        assert LiteLLMAnthropicToResponsesAPIAdapter.translate_responses_api_usage_to_anthropic_usage(None) == {
+            "input_tokens": 0,
+            "output_tokens": 0,
+        }
+
     def test_model_and_id_preserved(self):
         """Model and response ID from the Responses API are forwarded."""
         response = _make_mock_response(