diff --git a/litellm/caching/caching_handler.py b/litellm/caching/caching_handler.py
index 076eec79c14..1f844bfe29c 100644
--- a/litellm/caching/caching_handler.py
+++ b/litellm/caching/caching_handler.py
@@ -17,6 +17,7 @@ In each method it will call the appropriate method from caching.py
 import asyncio
 import datetime
 import inspect
+import json
 import time
 from collections.abc import AsyncGenerator, AsyncIterator, Awaitable, Callable, Generator, Mapping
 from typing import TYPE_CHECKING, Any, Final, Optional, TypeVar
@@ -159,6 +160,21 @@ async def _complete_cache_write_despite_cancellation(write_factory: Callable[[],
             raise
 
 
+def is_json_serializable(value: object) -> bool:
+    """
+    Whether `value` can be round-tripped through json.dumps.
+
+    Used to guard cache writes against provider-specific response wrappers
+    (e.g. synthetic streaming iterators) that aren't a recognized response
+    type but also aren't safe to hand to the cache backend as-is.
+    """
+    try:
+        json.dumps(value)
+    except TypeError:
+        return False
+    return True
+
+
 def create_cache_write_task(write_factory: Callable[[], Awaitable[None]]) -> "asyncio.Task[None]":
     with post_response_phase():
         task: Final = asyncio.create_task(_complete_cache_write_despite_cancellation(write_factory))
@@ -1100,19 +1116,7 @@ class LLMCachingHandler:
                             **new_kwargs,
                         )
                     )
-            else:
-                from litellm.llms.anthropic.pass_through.messages.fake_stream_iterator import (
-                    FakeAnthropicMessagesStreamIterator,
-                )
-
-                if isinstance(result, FakeAnthropicMessagesStreamIterator):
-                    # Synthetic streaming wrapper (e.g. websearch interception
-                    # short-circuit) around an already-served response. It is
-                    # not JSON-serializable and was never meant to be cached
-                    # as-is - caching it crashes the Redis/async cache backend
-                    # with "Object of type FakeAnthropicMessagesStreamIterator
-                    # is not JSON serializable" on every streaming request.
-                    return
+            elif is_json_serializable(result):
                 create_cache_write_task(lambda: cache.async_add_cache(result, **new_kwargs))
 
     def sync_set_cache(
diff --git a/tests/unit/caching/test_caching_handler.py b/tests/unit/caching/test_caching_handler.py
index 1599668839a..247508464e2 100644
--- a/tests/unit/caching/test_caching_handler.py
+++ b/tests/unit/caching/test_caching_handler.py
@@ -22,6 +22,7 @@ from litellm.caching.caching_handler import (
     CachingHandlerResponse,
     _is_chat_completion_cached_dict,
     _should_defer_streaming_cache_hit_callbacks,
+    is_json_serializable,
 )
 from litellm.caching.caching import LiteLLMCacheType
 from litellm.types.utils import CallTypes
@@ -130,6 +131,53 @@ async def test_async_set_get_cache(response):
     assert cached_response.cached_result.id == result.id
 
 
+def test_is_json_serializable():
+    """Plain values round-trip; arbitrary objects don't."""
+
+    class _NotSerializable:
+        pass
+
+    assert is_json_serializable({"a": 1}) is True
+    assert is_json_serializable("hello") is True
+    assert is_json_serializable(None) is True
+    assert is_json_serializable(_NotSerializable()) is False
+
+
+@pytest.mark.asyncio
+async def test_async_set_cache_skips_non_serializable_result():
+    """
+    Regression test: a response object that is neither one of the
+    recognized response types (ModelResponse, EmbeddingResponse, etc.) nor
+    JSON-serializable (e.g. a provider-specific synthetic streaming
+    iterator) must be skipped instead of being handed to the cache backend,
+    which would raise `TypeError: Object of type ... is not JSON
+    serializable`.
+    """
+    setup_cache()
+    caching_handler = LLMCachingHandler(
+        original_function=completion, request_kwargs={}, start_time=datetime.now()
+    )
+
+    class _UnserializableStreamWrapper:
+        """Stand-in for a provider-specific object that can't be cached."""
+
+        pass
+
+    result = _UnserializableStreamWrapper()
+    messages = [{"role": "user", "content": f"Unique message {datetime.now()}"}]
+
+    with patch(
+        "litellm.caching.caching_handler.create_cache_write_task"
+    ) as mock_create_cache_write_task:
+        await caching_handler.async_set_cache(
+            result=result,
+            original_function=litellm.acompletion,
+            kwargs={"messages": messages},
+        )
+
+        mock_create_cache_write_task.assert_not_called()
+
+
 @pytest.mark.asyncio
 async def test_async_log_cache_hit_on_callbacks():
     """