diff --git a/litellm/proxy/proxy_server.py b/litellm/proxy/proxy_server.py
index ad31ff33802..d4f405d0f64 100644
--- a/litellm/proxy/proxy_server.py
+++ b/litellm/proxy/proxy_server.py
@@ -885,6 +885,9 @@ async def proxy_startup_event(app: FastAPI):  # noqa: PLR0915
 
         await ProxyStartupEvent._update_default_team_member_budget()
 
+        ## SYNC UI SETTINGS ##
+        await ProxyStartupEvent._sync_ui_settings_to_general_settings()
+
     # Start background health checks AFTER models are loaded and index is built
     if use_background_health_checks:
         asyncio.create_task(
@@ -5639,6 +5642,41 @@ class ProxyStartupEvent:
                 teams=teams_pydantic_obj, user_api_key_dict=UserAPIKeyAuth(token=hash_token(master_key))  # type: ignore
             )
 
+    @classmethod
+    async def _sync_ui_settings_to_general_settings(cls):
+        """
+        Load persisted UI settings from the database and sync runtime flags
+        into general_settings so they take effect immediately after startup.
+        """
+        try:
+            import json
+
+            from litellm.proxy.ui_crud_endpoints.proxy_setting_endpoints import (
+                _RUNTIME_GENERAL_SETTINGS_FLAGS,
+            )
+
+            db_record = await prisma_client.db.litellm_uisettings.find_unique(
+                where={"id": "ui_settings"}
+            )
+            if db_record and db_record.ui_settings:
+                raw = db_record.ui_settings
+                ui_settings = json.loads(raw) if isinstance(raw, str) else dict(raw)
+                flags_to_sync = {
+                    k: ui_settings[k]
+                    for k in _RUNTIME_GENERAL_SETTINGS_FLAGS
+                    if k in ui_settings
+                }
+                if flags_to_sync:
+                    general_settings.update(flags_to_sync)
+                    verbose_proxy_logger.info(
+                        "Synced UI settings to general_settings on startup: %s",
+                        list(flags_to_sync.keys()),
+                    )
+        except Exception as e:
+            verbose_proxy_logger.debug(
+                "UI settings sync on startup skipped or failed: %s", e
+            )
+
     @classmethod
     async def initialize_scheduled_background_jobs(  # noqa: PLR0915
         cls,