diff --git a/litellm/litellm_core_utils/prompt_templates/common_utils.py b/litellm/litellm_core_utils/prompt_templates/common_utils.py
index 3c1b3cf964b..f92230f5755 100644
--- a/litellm/litellm_core_utils/prompt_templates/common_utils.py
+++ b/litellm/litellm_core_utils/prompt_templates/common_utils.py
@@ -13,6 +13,8 @@ from pathlib import Path
 from types import MappingProxyType
 from typing import TYPE_CHECKING, Any, Final, Literal, TypeVar, cast
 
+from pydantic import TypeAdapter
+
 import litellm
 from litellm import verbose_logger
 from litellm.router_utils.batch_utils import InMemoryFile
@@ -1805,6 +1807,33 @@ def cache_control_as_prompt_cache_breakpoint(block: _MarkedT) -> _MarkedT:
     )
 
 
+_BREAKPOINT_BLOCK_LIST_KEYS: Final = frozenset({"content", "tool_calls"})
+_BREAKPOINT_FIELDS: Final = TypeAdapter(Mapping[str, object])
+_BREAKPOINT_BLOCKS: Final = TypeAdapter(list[object])
+
+
+def _without_prompt_cache_breakpoint(value: object) -> object:
+    if not isinstance(value, Mapping):
+        return value
+    fields: Final = _BREAKPOINT_FIELDS.validate_python(value)
+    return {key: item for key, item in fields.items() if key != "prompt_cache_breakpoint"}
+
+
+def _breakpoints_stripped_from(key: str, value: object) -> object:
+    if key in _BREAKPOINT_BLOCK_LIST_KEYS and isinstance(value, list):
+        return [_without_prompt_cache_breakpoint(block) for block in _BREAKPOINT_BLOCKS.validate_python(value)]
+    return _without_prompt_cache_breakpoint(value) if key == "function" else value
+
+
+def without_prompt_cache_breakpoints(block: _MarkedT) -> _MarkedT:
+    """A message or tool definition with every ``prompt_cache_breakpoint`` removed: its own, its content parts',
+    its tool calls' and its ``function``'s."""
+    stripped: Final = {
+        key: _breakpoints_stripped_from(key, value) for key, value in block.items() if key != "prompt_cache_breakpoint"
+    }
+    return cast(_MarkedT, stripped)  # cast-ok: same block shape as the input minus the marker keys
+
+
 LITELLM_INTERNAL_MESSAGE_FIELDS: Final = frozenset({"thinking_blocks", "reasoning_content", "provider_specific_fields"})
 
 
diff --git a/litellm/llms/openai/chat/gpt_transformation.py b/litellm/llms/openai/chat/gpt_transformation.py
index a51704085bd..584cecc0f36 100644
--- a/litellm/llms/openai/chat/gpt_transformation.py
+++ b/litellm/llms/openai/chat/gpt_transformation.py
@@ -28,6 +28,7 @@ from litellm.litellm_core_utils.prompt_templates.common_utils import (
     hoist_images_from_tool_messages,
     system_messages_first,
     tool_with_sanitized_parameters,
+    without_prompt_cache_breakpoints,
 )
 from litellm.litellm_core_utils.prompt_templates.image_handling import (
     async_convert_url_to_base64,
@@ -474,7 +475,8 @@ class OpenAIGPTConfig(BaseLLMModelInfo, BaseConfig):
         A deployment that reads OpenAI's ``prompt_cache_breakpoint`` (gpt-5.6+ on
         api.openai.com, or one opted in through ``prompt_cache_options`` or the cost
         map) gets each Anthropic ``cache_control`` mark rewritten in place. Any other
-        endpoint keeps or strips the marks exactly as before.
+        endpoint keeps or strips the marks as before, and under drop_params also loses
+        every ``prompt_cache_breakpoint`` it cannot read.
         """
         from litellm.integrations.anthropic_cache_control_hook import AnthropicCacheControlHook
 
@@ -485,14 +487,24 @@ class OpenAIGPTConfig(BaseLLMModelInfo, BaseConfig):
         )
         if not reads_breakpoints and self._should_preserve_cache_control_for_endpoint(custom_llm_provider, api_base):
             return messages, tools
+        drops_breakpoints: Final = not reads_breakpoints and (
+            litellm.drop_params is True or litellm_params.get("drop_params") is True
+        )
         renamed: Final = (
             [AnthropicCacheControlHook.cache_control_as_prompt_cache_breakpoints(message) for message in messages]
             if reads_breakpoints
+            else [without_prompt_cache_breakpoints(message) for message in messages]
+            if drops_breakpoints
             else list(messages)
         )
-        return self.remove_cache_control_flag_from_messages_and_tools(
-            model=model, messages=renamed, tools=list(tools) if tools is not None else None
+        kept_tools: Final = (
+            None
+            if tools is None
+            else [without_prompt_cache_breakpoints(tool) for tool in tools]
+            if drops_breakpoints
+            else list(tools)
         )
+        return self.remove_cache_control_flag_from_messages_and_tools(model=model, messages=renamed, tools=kept_tools)
 
     def _sanitized_tools_update_for_openai(
         self,
diff --git a/tests/unit/llms/openai/chat/test_openai_gpt_transformation.py b/tests/unit/llms/openai/chat/test_openai_gpt_transformation.py
index a0a55df95e6..76faf338307 100644
--- a/tests/unit/llms/openai/chat/test_openai_gpt_transformation.py
+++ b/tests/unit/llms/openai/chat/test_openai_gpt_transformation.py
@@ -1592,6 +1592,43 @@ class TestOpenAIPromptCacheBreakpointChatPath:
         assert request["extra_body"] == {"prompt_cache_options": self.EXPLICIT}
         assert "prompt_cache_options" not in request
 
+    @pytest.mark.parametrize(
+        ("model", "drop_params", "sent"),
+        [("gpt-4.1", True, False), ("gpt-4.1", False, True), ("gpt-5.6", True, True)],
+        ids=["unread-dropped", "unread-sent-through", "read-kept"],
+    )
+    def test_drop_params_strips_breakpoints_only_where_the_model_cannot_read_them(
+        self, model: str, drop_params: bool, sent: bool
+    ):
+        marked_part: Final = {"type": "text", "text": "hi", "prompt_cache_breakpoint": self.EXPLICIT}
+        part: Final = {"type": "text", "text": "hi"}
+        call: Final = {"id": "c1", "type": "function", "function": {"name": "f", "arguments": "{}"}}
+        function: Final = {"name": "f", "parameters": {"type": "object"}}
+        marked: Final = {"prompt_cache_breakpoint": self.EXPLICIT}
+
+        request = OpenAIGPTConfig().transform_request(
+            model=model,
+            messages=[
+                {"role": "user", "content": [marked_part]},
+                {"role": "assistant", "content": "ok", **marked, "tool_calls": [{**call, **marked}]},
+                {"role": "tool", "tool_call_id": "c1", "content": "done"},
+            ],
+            optional_params={"tools": [{"type": "function", "function": {**function, **marked}}, {"type": "function", "function": function, **marked}]},
+            litellm_params={"custom_llm_provider": "openai", "drop_params": drop_params},
+            headers={},
+        )
+
+        mark: Final = marked if sent else {}
+        assert request["messages"] == [
+            {"role": "user", "content": [marked_part if sent else part]},
+            {"role": "assistant", "content": "ok", **mark, "tool_calls": [{**call, **mark}]},
+            {"role": "tool", "tool_call_id": "c1", "content": "done"},
+        ]
+        assert request["tools"] == [
+            {"type": "function", "function": {**function, **mark}},
+            {"type": "function", "function": function, **mark},
+        ]
+
 
 _ARTIFACT_FIELD_PATTERN: Final = r'^(?!__.*__$)[^\p{Cc}\p{Cf}\p{Zl}\p{Zp}"\\./[\]]{1,200}$'