diff --git a/tests/e2e/guardrails/test_apply_guardrail_e2e.py b/tests/e2e/guardrails/test_apply_guardrail_e2e.py
index ee691db22da..efbdd6ca97e 100644
--- a/tests/e2e/guardrails/test_apply_guardrail_e2e.py
+++ b/tests/e2e/guardrails/test_apply_guardrail_e2e.py
@@ -18,6 +18,12 @@ pytestmark = pytest.mark.e2e
 
 
 class TestApplyGuardrailEndpoint:
+    @pytest.mark.skip(
+        reason=(
+            "LIT-5120: flaky - /apply_guardrail round-robins onto a pod that has not synced the "
+            "guardrail the test just created and 404s (6 of ~21 stage runs since Jul 28)"
+        )
+    )
     @pytest.mark.covers(
         "guardrail.litellm_content_filter.apply_endpoint.blocks",
         "guardrail.litellm_content_filter.apply_endpoint.allows",
diff --git a/tests/e2e/logging/test_datadog_log_e2e.py b/tests/e2e/logging/test_datadog_log_e2e.py
index 94811c6217e..368fb187424 100644
--- a/tests/e2e/logging/test_datadog_log_e2e.py
+++ b/tests/e2e/logging/test_datadog_log_e2e.py
@@ -141,6 +141,12 @@ class TestDataDogLogDelivery:
             events, model_group=CHEAP_ANTHROPIC_MODEL, call_type="acompletion", cost_anchor=outcome.response_cost
         )
 
+    @pytest.mark.skip(
+        reason=(
+            "LIT-5121: flaky - the /v1/messages log event missed the Datadog poll window on the "
+            "2026-08-02 stage run; skipped while delivery vs ingest-latency is investigated"
+        )
+    )
     @pytest.mark.covers("logging.datadog.success.exports_metric", exercised_on=["messages"])
     def test_messages_emits_one_log_event(
         self, client: LoggingClient, dd_logs: DdLogsReader, resources: ResourceManager