diff --git a/litellm/proxy/common_request_processing.py b/litellm/proxy/common_request_processing.py
index 97de2488b8d..59c44ab8101 100644
--- a/litellm/proxy/common_request_processing.py
+++ b/litellm/proxy/common_request_processing.py
@@ -3894,7 +3894,7 @@ class ProxyBaseLLMRequestProcessing:
         # pure overhead on the streaming hot path (the default config).
         caps: Final = ProxyLogging._callback_capabilities()
         cost_injection_enabled: Final = bool(getattr(litellm, "include_cost_in_streaming_usage", False))
-        fast_path = not caps.has_streaming_chunk_override and not caps.has_guardrail and not cost_injection_enabled
+        fast_path = not caps.has_streaming_chunk_override and not caps.has_streaming_guardrail and not cost_injection_enabled
         debug_enabled: Final = verbose_proxy_logger.isEnabledFor(logging.DEBUG)
         stream_completed = False
         client_disconnected = False
diff --git a/litellm/proxy/utils.py b/litellm/proxy/utils.py
index ea294b76e92..2f2e59f6ee4 100644
--- a/litellm/proxy/utils.py
+++ b/litellm/proxy/utils.py
@@ -78,7 +78,7 @@ from litellm.proxy.common_utils.openai_error_payload import (
     with_litellm_call_id,
 )
 from litellm.proxy.spend_tracking.spend_log_error_logger import spend_log_error
-from litellm.types.guardrails import GuardrailEventHooks
+from litellm.types.guardrails import GuardrailEventHooks, Mode
 from litellm.types.proxy.model_listing import ModelInfoResponse
 from litellm.types.utils import MCP_GUARDRAIL_CALL_TYPES, CallTypes, CallTypesLiteral, ModelInfo, Usage
 
@@ -1128,6 +1128,11 @@ class _CallbackCapabilities:
     has_iterator_override: bool = False
     has_streaming_chunk_override: bool = False
     has_guardrail: bool = False
+    # True when any CustomGuardrail is configured for a response-side hook
+    # (not exclusively pre_call / pre_mcp_call). Used by streaming fast paths.
+    has_streaming_guardrail: bool = False
+    # True when any CustomGuardrail can run on during_call.
+    has_during_call_guardrail: bool = False
     has_pre_call_override: bool = False
     has_content_enforcer: bool = False
     has_moderation_override: bool = False
@@ -1151,6 +1156,68 @@ def _overrides_moderation_hook(callback: CustomLogger) -> bool:
     return _overrides_hook(callback, "async_moderation_hook")
 
 
+
+_PRE_CALL_ONLY_HOOKS: Final = frozenset(
+    {
+        GuardrailEventHooks.pre_call.value,
+        GuardrailEventHooks.pre_mcp_call.value,
+    }
+)
+
+
+def _normalize_guardrail_hook_name(hook: object) -> str:
+    if isinstance(hook, GuardrailEventHooks):
+        return hook.value
+    return str(hook)
+
+
+def _guardrail_configured_hooks(guardrail: CustomGuardrail) -> frozenset[str] | None:
+    """Return the hook names this guardrail is configured for.
+
+    ``None`` means unrestricted (``event_hook`` unset), which matches every
+    lifecycle event — including response / streaming hooks.
+    """
+    event_hook = guardrail.event_hook
+    if event_hook is None:
+        return None
+    if isinstance(event_hook, Mode):
+        hooks: set[str] = set()
+        for tag_value in event_hook.tags.values():
+            if isinstance(tag_value, list):
+                hooks.update(_normalize_guardrail_hook_name(value) for value in tag_value)
+            else:
+                hooks.add(_normalize_guardrail_hook_name(tag_value))
+        if event_hook.default:
+            default_list = (
+                event_hook.default if isinstance(event_hook.default, list) else [event_hook.default]
+            )
+            hooks.update(_normalize_guardrail_hook_name(value) for value in default_list)
+        return frozenset(hooks)
+    if isinstance(event_hook, list):
+        return frozenset(_normalize_guardrail_hook_name(hook) for hook in event_hook)
+    return frozenset({_normalize_guardrail_hook_name(event_hook)})
+
+
+def _guardrail_affects_streaming(guardrail: CustomGuardrail) -> bool:
+    """True unless the guardrail is request-only (``pre_call`` / ``pre_mcp_call``).
+
+    Streaming fast-path gates must not treat a purely pre-call guardrail as a
+    reason to pay the per-chunk ``async_post_call_streaming_hook`` path.
+    """
+    hooks = _guardrail_configured_hooks(guardrail)
+    if hooks is None:
+        return True
+    return bool(hooks - _PRE_CALL_ONLY_HOOKS)
+
+
+def _guardrail_affects_during_call(guardrail: CustomGuardrail) -> bool:
+    """True if this guardrail can run on the ``during_call`` event."""
+    hooks = _guardrail_configured_hooks(guardrail)
+    if hooks is None:
+        return True
+    return GuardrailEventHooks.during_call.value in hooks
+
+
 _LISTED_MODEL_NAMES: Final = TypeAdapter(tuple[str, ...])
 
 
@@ -2787,6 +2854,8 @@ class ProxyLogging:
         has_iterator_override = False
         has_streaming_chunk_override = False
         has_guardrail = False
+        has_streaming_guardrail = False
+        has_during_call_guardrail = False
         has_pre_call_override = False
         has_content_enforcer = False
         has_moderation_override = False
@@ -2808,6 +2877,10 @@ class ProxyLogging:
                 continue
             if isinstance(resolved, CustomGuardrail):
                 has_guardrail = True
+                if _guardrail_affects_streaming(resolved):
+                    has_streaming_guardrail = True
+                if _guardrail_affects_during_call(resolved):
+                    has_during_call_guardrail = True
             elif _overrides_moderation_hook(resolved):
                 has_moderation_override = True
             # Use the same leaf-class ``__dict__`` check as the other hook
@@ -2822,7 +2895,15 @@ class ProxyLogging:
             if "async_post_call_streaming_iterator_hook" in cls_attrs:
                 has_iterator_override = True
                 iterator_overrides.append((resolved, "override"))
-            elif "apply_guardrail" in cls_attrs and not getattr(resolved, "use_native_lifecycle_hooks", False):
+            elif (
+                "apply_guardrail" in cls_attrs
+                and not getattr(resolved, "use_native_lifecycle_hooks", False)
+                and (
+                    not isinstance(resolved, CustomGuardrail)
+                    or _guardrail_affects_streaming(resolved)
+                )
+            ):
+                # pre_call-only guardrails never scan the response stream
                 iterator_overrides.append((resolved, "apply_guardrail"))
             # Walk the MRO for ``async_post_call_streaming_hook`` rather than
             # using the leaf-class ``__dict__`` check used by the other flags:
@@ -2852,6 +2933,8 @@ class ProxyLogging:
             or any(kind == "apply_guardrail" for _, kind in iterator_overrides),
             has_streaming_chunk_override=has_streaming_chunk_override,
             has_guardrail=has_guardrail,
+            has_streaming_guardrail=has_streaming_guardrail,
+            has_during_call_guardrail=has_during_call_guardrail,
             has_pre_call_override=has_pre_call_override,
             has_content_enforcer=has_content_enforcer,
             has_moderation_override=has_moderation_override,
@@ -2885,14 +2968,14 @@ class ProxyLogging:
     @staticmethod
     def has_streaming_callbacks() -> bool:
         caps: Final = ProxyLogging._callback_capabilities()
-        return caps.has_iterator_override or caps.has_streaming_chunk_override or caps.has_guardrail
+        return caps.has_iterator_override or caps.has_streaming_chunk_override or caps.has_streaming_guardrail
 
     @staticmethod
     def has_streaming_chunk_hook_overrides() -> bool:
         """True iff any callback overrides ``async_post_call_streaming_hook``
         (the per-chunk hook, distinct from the iterator wrapper)."""
         caps: Final = ProxyLogging._callback_capabilities()
-        return caps.has_streaming_chunk_override or caps.has_guardrail
+        return caps.has_streaming_chunk_override or caps.has_streaming_guardrail
 
     def needs_iterator_wrap(self) -> bool:
         """Whether ``async_data_generator`` needs to wrap the upstream stream
@@ -2907,11 +2990,11 @@ class ProxyLogging:
         method for the same reason as :py:meth:`needs_iterator_wrap`.
         """
         caps: Final = ProxyLogging._callback_capabilities()
-        return caps.has_streaming_chunk_override or caps.has_guardrail
+        return caps.has_streaming_chunk_override or caps.has_streaming_guardrail
 
     @staticmethod
     def has_during_call_guardrails() -> bool:
-        return ProxyLogging._callback_capabilities().has_guardrail
+        return ProxyLogging._callback_capabilities().has_during_call_guardrail
 
     async def during_call_hook(
         self,
@@ -2920,7 +3003,7 @@ class ProxyLogging:
         call_type: CallTypesLiteral,
     ):
         caps: Final = ProxyLogging._callback_capabilities()
-        if not caps.has_guardrail and not caps.has_moderation_override:
+        if not caps.has_during_call_guardrail and not caps.has_moderation_override:
             return data
         # Step 1: Collect all guardrail tasks to run in parallel
         guardrail_tasks: Final = []
@@ -3826,7 +3909,7 @@ class ProxyLogging:
         # chunk so paying it per chunk for no-op callbacks dominated stream
         # CPU time even after the iterator-chain fix.
         caps: Final = ProxyLogging._callback_capabilities()
-        if not caps.has_streaming_chunk_override and not caps.has_guardrail:
+        if not caps.has_streaming_chunk_override and not caps.has_streaming_guardrail:
             return response
 
         from litellm.proxy.proxy_server import llm_router
@@ -3844,7 +3927,7 @@ class ProxyLogging:
             _cached_guardrail_data: dict | None = None
             _guardrail_data_computed = False
             pipeline_gated: Final = (
-                stream_gated_guardrail_names(data, user_api_key_dict) if caps.has_guardrail else frozenset()
+                stream_gated_guardrail_names(data, user_api_key_dict) if caps.has_streaming_guardrail else frozenset()
             )
 
             for callback in litellm.callbacks:
diff --git a/tests/test_litellm/proxy/test_proxy_logging_hook_detection.py b/tests/test_litellm/proxy/test_proxy_logging_hook_detection.py
index 9eb89b2f301..a14d2c920f6 100644
--- a/tests/test_litellm/proxy/test_proxy_logging_hook_detection.py
+++ b/tests/test_litellm/proxy/test_proxy_logging_hook_detection.py
@@ -52,10 +52,24 @@ def test_has_streaming_callbacks_uses_custom_logger_detection(monkeypatch):
 
 
 def test_has_streaming_callbacks_detects_guardrails(monkeypatch):
+    # Unrestricted CustomGuardrail (event_hook=None) matches every lifecycle
+    # event, including response / streaming hooks.
     monkeypatch.setattr(litellm, "callbacks", [CustomGuardrail()])
     assert ProxyLogging.has_streaming_callbacks() is True
 
 
+def test_has_streaming_callbacks_ignores_pre_call_only_guardrails(monkeypatch):
+    monkeypatch.setattr(
+        litellm,
+        "callbacks",
+        [CustomGuardrail(event_hook=GuardrailEventHooks.pre_call, default_on=True)],
+    )
+    assert ProxyLogging.has_streaming_callbacks() is False
+    caps = ProxyLogging._callback_capabilities()
+    assert caps.has_guardrail is True
+    assert caps.has_streaming_guardrail is False
+
+
 @pytest.mark.asyncio
 async def test_post_call_response_headers_hook_returns_early_without_callbacks(
     monkeypatch,
diff --git a/tests/test_litellm/proxy/utils/proxy_logging/test_callback_capabilities_class.py b/tests/test_litellm/proxy/utils/proxy_logging/test_callback_capabilities_class.py
index 75a91177f00..97a027dbb86 100644
--- a/tests/test_litellm/proxy/utils/proxy_logging/test_callback_capabilities_class.py
+++ b/tests/test_litellm/proxy/utils/proxy_logging/test_callback_capabilities_class.py
@@ -271,27 +271,73 @@ def test_needs_per_chunk_streaming_hook_error_raises(proxy_logging, monkeypatch)
 
 def test_has_during_call_guardrails_truth_table(monkeypatch, mock_callbacks_disabled):
     from litellm.integrations.custom_guardrail import CustomGuardrail
+    from litellm.types.guardrails import GuardrailEventHooks
 
-    class _G(CustomGuardrail):
+    class _PreCallOnly(CustomGuardrail):
         def __init__(self):
-            super().__init__(guardrail_name="g", event_hook="pre_call")
+            super().__init__(guardrail_name="g-pre", event_hook=GuardrailEventHooks.pre_call)
+
+    class _DuringCall(CustomGuardrail):
+        def __init__(self):
+            super().__init__(guardrail_name="g-during", event_hook=GuardrailEventHooks.during_call)
 
     snapshot = {
         "empty_false": ProxyLogging.has_during_call_guardrails(),
     }
-    monkeypatch.setattr(litellm, "callbacks", [_G()])
+    monkeypatch.setattr(litellm, "callbacks", [_PreCallOnly()])
     ProxyLogging._callback_capabilities_cache.clear()
-    snapshot["with_guardrail_true"] = ProxyLogging.has_during_call_guardrails()
+    snapshot["pre_call_only_false"] = ProxyLogging.has_during_call_guardrails()
+    monkeypatch.setattr(litellm, "callbacks", [_DuringCall()])
+    ProxyLogging._callback_capabilities_cache.clear()
+    snapshot["with_during_call_true"] = ProxyLogging.has_during_call_guardrails()
     monkeypatch.setattr(litellm, "callbacks", [_PlainLogger()])
     ProxyLogging._callback_capabilities_cache.clear()
     snapshot["only_plain_logger_false"] = ProxyLogging.has_during_call_guardrails()
     assert snapshot == {
         "empty_false": False,
-        "with_guardrail_true": True,
+        "pre_call_only_false": False,
+        "with_during_call_true": True,
         "only_plain_logger_false": False,
     }
 
 
+def test_streaming_fast_path_ignores_pre_call_only_guardrails(monkeypatch, mock_callbacks_disabled):
+    """pre_call-only CustomGuardrails must not disable the streaming fast path."""
+    from litellm.integrations.custom_guardrail import CustomGuardrail
+    from litellm.types.guardrails import GuardrailEventHooks
+
+    class _PreCallOnly(CustomGuardrail):
+        def __init__(self):
+            super().__init__(
+                guardrail_name="pre-only",
+                event_hook=GuardrailEventHooks.pre_call,
+                default_on=True,
+            )
+
+    class _PostCall(CustomGuardrail):
+        def __init__(self):
+            super().__init__(
+                guardrail_name="post",
+                event_hook=GuardrailEventHooks.post_call,
+                default_on=True,
+            )
+
+    monkeypatch.setattr(litellm, "callbacks", [_PreCallOnly()])
+    ProxyLogging._callback_capabilities_cache.clear()
+    caps = ProxyLogging._callback_capabilities()
+    assert caps.has_guardrail is True
+    assert caps.has_streaming_guardrail is False
+    assert ProxyLogging.has_streaming_callbacks() is False
+    assert ProxyLogging.has_streaming_chunk_hook_overrides() is False
+
+    monkeypatch.setattr(litellm, "callbacks", [_PreCallOnly(), _PostCall()])
+    ProxyLogging._callback_capabilities_cache.clear()
+    caps = ProxyLogging._callback_capabilities()
+    assert caps.has_guardrail is True
+    assert caps.has_streaming_guardrail is True
+    assert ProxyLogging.has_streaming_callbacks() is True
+
+
 def test_has_during_call_guardrails_resolution_error_raises(monkeypatch):
     monkeypatch.setattr(litellm, "callbacks", ["x"])
     monkeypatch.setattr(
diff --git a/tests/test_litellm/proxy/utils/proxy_logging/test_callback_capabilities_dataclass.py b/tests/test_litellm/proxy/utils/proxy_logging/test_callback_capabilities_dataclass.py
index 931c832732e..68e47337fb9 100644
--- a/tests/test_litellm/proxy/utils/proxy_logging/test_callback_capabilities_dataclass.py
+++ b/tests/test_litellm/proxy/utils/proxy_logging/test_callback_capabilities_dataclass.py
@@ -16,6 +16,8 @@ def test_callback_capabilities_default_values():
         "has_iterator_override": caps.has_iterator_override,
         "has_streaming_chunk_override": caps.has_streaming_chunk_override,
         "has_guardrail": caps.has_guardrail,
+        "has_streaming_guardrail": caps.has_streaming_guardrail,
+        "has_during_call_guardrail": caps.has_during_call_guardrail,
         "has_pre_call_override": caps.has_pre_call_override,
         "iterator_overrides": caps.iterator_overrides,
         "resolved_callbacks": caps.resolved_callbacks,
@@ -25,6 +27,8 @@ def test_callback_capabilities_default_values():
         "has_iterator_override": False,
         "has_streaming_chunk_override": False,
         "has_guardrail": False,
+        "has_streaming_guardrail": False,
+        "has_during_call_guardrail": False,
         "has_pre_call_override": False,
         "iterator_overrides": (),
         "resolved_callbacks": (),